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Cellular Component

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GO ID	Description
GO:0005737	cytoplasm
GO:0005615	extracellular space
GO:0005829	cytosol
GO:0016020	membrane
GO:0012505	endomembrane system
GO:0005886	plasma membrane
GO:0031234	extrinsic component of cytoplasmic side of plasma membrane

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Molecular Function

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GO ID	Description
GO:0005089	Rho guanyl-nucleotide exchange factor activity
GO:0035091	phosphatidylinositol binding
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0008289	lipid binding

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Biological Process

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GO ID	Description
GO:0051056	regulation of small GTPase mediated signal transduction
GO:0043547	positive regulation of GTPase activity
GO:0043065	positive regulation of apoptotic process
GO:0035025	positive regulation of Rho protein signal transduction
GO:0035023	regulation of Rho protein signal transduction
GO:0035556	intracellular signal transduction

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Reactome

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Reactome ID	Description
R-HSA-416482	G alpha (12/13) signalling events
R-HSA-194840	Rho GTPase cycle
R-HSA-193648	NRAGE signals death through JNK

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KEGG

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Field	Data
Localization in this study:	plasma_membrane, vesicles
Localization in the literature:	Golgi