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Cellular Component

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GO ID	Description
GO:0005737	cytoplasm
GO:0043197	dendritic spine
GO:0030027	lamellipodium
GO:0031410	cytoplasmic vesicle
GO:0005634	nucleus
GO:0016020	membrane
GO:0045211	postsynaptic membrane
GO:0045335	phagocytic vesicle
GO:0014069	postsynaptic density
GO:0045202	synapse
GO:0005886	plasma membrane
GO:0044327	dendritic spine head
GO:0042995	cell projection
GO:0005829	cytosol
GO:0030054	cell junction

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Molecular Function

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GO ID	Description
GO:0048365	Rac GTPase binding
GO:0005096	GTPase activator activity
GO:0042802	identical protein binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity

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Biological Process

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GO ID	Description
GO:0051056	regulation of small GTPase mediated signal transduction
GO:0021816	extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration
GO:0043547	positive regulation of GTPase activity
GO:0007399	nervous system development
GO:0034446	substrate adhesion-dependent cell spreading
GO:0051014	actin filament severing
GO:0048812	neuron projection morphogenesis
GO:0007165	signal transduction
GO:2001223	negative regulation of neuron migration
GO:0046847	filopodium assembly
GO:0060996	dendritic spine development
GO:0003363	lamellipodium assembly involved in ameboidal cell migration

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Reactome

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Reactome ID	Description
R-HSA-5663220	RHO GTPases Activate Formins
R-HSA-194840	Rho GTPase cycle
R-HSA-428543	Inactivation of CDC42 and RAC1

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KEGG

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Kegg ID	Description
hsa04360	Axon guidance

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Field	Data
Localization in this study:	plasma_membrane, puncta
Localization in the literature:	nucleus plasma membrane