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Cellular Component

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GO ID	Description
GO:0005737	cytoplasm
GO:0043234	protein complex
GO:0070062	extracellular exosome
GO:0005829	cytosol
GO:0016020	membrane
GO:0045211	postsynaptic membrane
GO:0014069	postsynaptic density
GO:0045202	synapse
GO:0005886	plasma membrane
GO:0030054	cell junction

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Molecular Function

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GO ID	Description
GO:0005089	Rho guanyl-nucleotide exchange factor activity
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0016301	kinase activity
GO:0005096	GTPase activator activity
GO:0019899	enzyme binding
GO:0000166	nucleotide binding
GO:0004674	protein serine/threonine kinase activity
GO:0016740	transferase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding

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Biological Process

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GO ID	Description
GO:0071222	cellular response to lipopolysaccharide
GO:0051056	regulation of small GTPase mediated signal transduction
GO:0060268	negative regulation of respiratory burst
GO:0016310	phosphorylation
GO:0060313	negative regulation of blood vessel remodeling
GO:2000378	negative regulation of reactive oxygen species metabolic process
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0048008	platelet-derived growth factor receptor signaling pathway
GO:0003014	renal system process
GO:0007165	signal transduction
GO:0035556	intracellular signal transduction
GO:0035023	regulation of Rho protein signal transduction
GO:0032496	response to lipopolysaccharide
GO:0046777	protein autophosphorylation
GO:0050766	positive regulation of phagocytosis
GO:0050728	negative regulation of inflammatory response
GO:0043547	positive regulation of GTPase activity
GO:0050885	neuromuscular process controlling balance
GO:0065002	intracellular protein transmembrane transport
GO:0030336	negative regulation of cell migration
GO:0006468	protein phosphorylation
GO:0030036	actin cytoskeleton organization
GO:0060216	definitive hemopoiesis
GO:0048872	homeostasis of number of cells
GO:0042472	inner ear morphogenesis
GO:0007420	brain development
GO:0051726	regulation of cell cycle
GO:0043314	negative regulation of neutrophil degranulation
GO:0002692	negative regulation of cellular extravasation
GO:0043114	regulation of vascular permeability
GO:0051171	regulation of nitrogen compound metabolic process

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Reactome

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Reactome ID	Description
R-HSA-5655302	Signaling by FGFR1 in disease
R-HSA-194840	Rho GTPase cycle
R-HSA-1839117	Signaling by cytosolic FGFR1 fusion mutants

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KEGG

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Kegg ID	Description
hsa05200	Pathways in cancer
hsa05220	Chronic myeloid leukemia

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Field	Data
Localization in this study:	actin, plasma_membrane
Localization in the literature:	plasma membrane Golgi cytosolic