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Cellular Component

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GO ID	Description
GO:0005737	cytoplasm
GO:0015629	actin cytoskeleton
GO:0005634	nucleus
GO:0016020	membrane
GO:0005938	cell cortex
GO:0048471	perinuclear region of cytoplasm
GO:0005829	cytosol
GO:0005884	actin filament

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Molecular Function

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GO ID	Description
GO:0005089	Rho guanyl-nucleotide exchange factor activity
GO:0051018	protein kinase A binding
GO:0004871	signal transducer activity
GO:0005078	MAP-kinase scaffold activity
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0017048	Rho GTPase binding
GO:0032947	protein complex scaffold activity
GO:0005515	protein binding
GO:0004691	cAMP-dependent protein kinase activity
GO:0046872	metal ion binding

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Biological Process

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GO ID	Description
GO:0007507	heart development
GO:0006468	protein phosphorylation
GO:0010611	regulation of cardiac muscle hypertrophy
GO:0043547	positive regulation of GTPase activity
GO:1900169	regulation of glucocorticoid mediated signaling pathway
GO:0051056	regulation of small GTPase mediated signal transduction
GO:0086023	adrenergic receptor signaling pathway involved in heart process
GO:0045859	regulation of protein kinase activity
GO:0060297	regulation of sarcomere organization
GO:0060348	bone development
GO:0043065	positive regulation of apoptotic process
GO:0035025	positive regulation of Rho protein signal transduction
GO:0071875	adrenergic receptor signaling pathway
GO:0051168	nuclear export
GO:0035023	regulation of Rho protein signal transduction
GO:0055007	cardiac muscle cell differentiation
GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway
GO:0035556	intracellular signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

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Reactome

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Reactome ID	Description
R-HSA-416482	G alpha (12/13) signalling events
R-HSA-194840	Rho GTPase cycle
R-HSA-193648	NRAGE signals death through JNK

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KEGG

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Field	Data
Localization in this study:	cytosolic
Localization in the literature:	cytosolic plasma membrane