Field Data
UniProt Accession: Q14CB8
Gene Name: ARHGAP19
Gene Synonim:
GAP/GEF: GAP
Description: Rho GTPase-activating protein 19 (Rho-type GTPase-activating protein 19)
Keywords: Acetylation;Alternative splicing;Complete proteome;GTPase activation;Nucleus;Phosphoprotein;Polymorphism;Reference proteome
Entrez ID: 84986
Ensembl Gene ID: ENSG00000213390
Ensembl Protein ID: ENSP00000360066
Our Specificity RhoA
Literature Specificity RhoA
Literature reference
Domain Composition:

Cellular Component

GO ID Description
GO:0005634nucleus
GO:0005829cytosol

Molecular Function

GO ID Description
GO:0005096GTPase activator activity

Biological Process

GO ID Description
GO:0051056regulation of small GTPase mediated signal transduction
GO:0007165signal transduction
GO:0043547positive regulation of GTPase activity

Reactome

Reactome ID Description
R-HSA-194840Rho GTPase cycle

KEGG

Field Data
Localization in this study: nucleus
Localization in the literature: nucleus

Confocal Images

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Cytochalasin D Screen Negative

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organism orgs
Organism: Homo sapiens

Nucleotide Sequence

>ARHGAP19
atggcgactgaggcacagagtgaaggggaggtgccagcccgcgaatccggccggagtgat
gccatctgcagttttgtgatctgcaatgattcttcccttcgaggtcagcccattatcttt
aatcctgacttttttgtggagaaactccgacatgagaaacctgagattttcactgagttg
gtggtcagcaatatcacaaggctcatcgatttacctggaactgagttggctcagctgatg
ggggaagtggaccttaagttgcctggcggggctggcccagcatcaggattcttccggtct
ctcatgtctctcaagcgaaaggaaaaaggagtgatatttgggtccccactgacggaggaa
ggcattgcccagatataccaactgattgagtatctacacaaaaacttgcgagtagagggt
ttgtttagagtaccgggtaatagtgtccgacagcagattttaagggatgctctcaataat
ggaactgacattgacttggaatcaggggaatttcactcaaatgatgttgccactttgctg
aagatgtttctaggagagttgccggagcctctgctgacacataaacacttcaatgcacac
ctcaaaatcgctgatttgatgcagtttgatgataaaggaaacaagaccaatataccagac
aaggaccggcaaattgaggctctccagttgctcttcctcattctccctcctcctaatcgt
aatttgctgaagttattgcttgatctcctataccagacagcaaagaaacaagacaagaac
aagatgtcagcctataaccttgcccttatgtttgcaccccacgtcctgtggccaaaaaat
gtcactgcaaatgaccttcaggagaatatcacaaagttaaacagtgggatggcttttatg
attaaacactcccagaaactttttaaggctcctgcttacattcgggagtgtgcgagattg
cactatttgggatccagaactcaggcatcaaaggatgaccttgacctcatagcttcatgt
catactaagtcctttcagctggcaaagtctcagaaacggaaccgggtagattcctgccct
caccaggaggagacccagcaccatacggaagaggcactgagagagctgtttcaacacgtt
catgatatgccagagtcagcaaagaagaaacaacttattagacagtttaataagcaatca
ttgacccagacaccagggcgagaaccttctacttcccaggtacaaaagagggctcgttcg
cgctccttcagtgggcttattaagcggaaggtcctgggaaatcagatgatgtcagaaaag
aaaaagaagaaccctactccagaatctgtggccattggtgaattgaagggaaccagcaaa
gaaaataggaacttattattttctggctctccagctgtcacgatgacaccaacaagattg
aagtggtctgaagggaagaaagaggggaaaaaaggatttctcttaatta

Protein Sequence

>ARHGAP19
MATEAQSEGEVPARESGRSDAICSFVICNDSSLRGQPIIFNPDFFVEKLRHEKPEIFTEL
VVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPASGFFRSLMSLKRKEKGVIFGSPLTEE
GIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLL
KMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNR
NLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFM
IKHSQKLFKAPAYIRECARLHYLGSRTQASKDDLDLIASCHTKSFQLAKSQKRNRVDSCP
HQEETQHHTEEALRELFQHVHDMPESAKKKQLIRQFNKQSLTQTPGREPSTSQVQKRARS
RSFSGLIKRKVLGNQMMSEKKKKNPTPESVAIGELKGTSKENRNLLFSGSPAVTMTPTRL
KWSEGKKEGKKGFLLI

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