Field Data
UniProt Accession: Q15311
Gene Name: RALBP1
Gene Synonim: RLIP1, RLIP76
GAP/GEF: GAP
Description: RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (Ral-interacting protein 1)
Keywords: 3D-structure;Acetylation;Complete proteome;Direct protein sequencing;GTPase activation;Membrane;Phosphoprotein;Polymorphism;Reference proteome;Transport
Entrez ID: 10928
Ensembl Gene ID: ENSG00000017797
Ensembl Protein ID: ENSP00000372924
Our Specificity Rac1
Literature Specificity Cdc42
Literature reference
Domain Composition:

Cellular Component

GO ID Description
GO:0005829cytosol
GO:0016020membrane

Molecular Function

GO ID Description
GO:0005515protein binding
GO:0043492ATPase activity, coupled to movement of substances
GO:0005096GTPase activator activity
GO:0048365Rac GTPase binding
GO:0022857transmembrane transporter activity
GO:0016887ATPase activity
GO:0017160Ral GTPase binding

Biological Process

GO ID Description
GO:0051056regulation of small GTPase mediated signal transduction
GO:0006897endocytosis
GO:0006935chemotaxis
GO:0006810transport
GO:0007165signal transduction
GO:0007264small GTPase mediated signal transduction
GO:0043087regulation of GTPase activity
GO:0055085transmembrane transport
GO:0043547positive regulation of GTPase activity

Reactome

Reactome ID Description
R-HSA-194840Rho GTPase cycle

KEGG

Kegg ID Description
hsa05212Pancreatic cancer
hsa04014Ras signaling pathway
hsa05200Pathways in cancer
Field Data
Localization in this study: cytosolic
Localization in the literature: mitochondria nucleus

Confocal Images

Card image cap

Cytochalasin D Screen Negative

Card image cap
Card image cap
organism orgs
Organism: Homo sapiens

Nucleotide Sequence

>RALBP1
atgactgagtgcttcctgccccccaccagcagccccagtgaacaccgcagggtggagcat
ggcagcgggcttacccggacccccagctctgaagagatcagccctactaagtttcctgga
ttgtaccgcactggcgagccctcacctccccatgacatcctccatgagcctcctgatgta
gtgtctgatgatgagaaagatcatgggaagaaaaaagggaaatttaagaaaaaggaaaag
aggactgaaggctatgcagcctttcaggaagatagctctggagatgaggcagaaagtcct
tctaaaatgaagaggtccaagggaatccatgttttcaagaagcccagcttttctaaaaag
aaggaaaaggattttaaaataaaagagaaacccaaagaagaaaagcataaagaagaaaag
cacaaagaagaaaaacataaagagaagaagtcaaaagacttgacagcagctgatgttgtt
aaacagtggaaggaaaagaagaaaaagaaaaagccaattcaggagccagaggtgcctcag
attgatgttccaaatctcaaacccatttttggaattcctttggctgatgcagtagagagg
accatgatgtatgatggcattcggctgccagccgttttccgtgaatgtatagattacgta
gagaagtatggcatgaagtgtgaaggcatctacagagtatcaggaattaaatcaaaggtg
gatgagctaaaagcagcctatgaccgggaggagtctacaaacttggaagactatgagcct
aacactgtagccagtttgctgaagcagtatttgcgagaccttccagagaatttgcttacc
aaagagcttatgcccagatttgaagaggcttgtgggaggaccacggagactgagaaagtg
caggaattccagcgtttactcaaagaactgccagaatgtaactatcttctgatttcttgg
ctcattgtgcacatggaccatgtcattgcaaaggaactggaaacaaaaatgaatatacag
aacatttctatagtgctcagcccaactgtgcagatcagcaatcgagtcctgtatgtgttt
ttcacacatgtgcaagaactctttggaaatgtggtactaaagcaagtgatgaaacctctg
cgatggtctaacatggccacgatgcccacgctgccagagacccaggcgggcatcaaggag
gagatcaggagacaggagtttcttttgaattgtttacatcgagatctgcagggtgggata
aaggatttgtctaaagaagaaagattatgggaagtacaaagaattttgacagccctcaaa
agaaaactgagagaagctaaaagacaggagtgtgaaaccaagattgcacaagagatagcc
agtctttcaaaagaggatgtttccaaagaagagatgaatgaaaatgaagaagttataaat
attctccttgctcaggagaatgagatcctgactgaacaggaggagctcctggccatggag
cagtttctgcgccggcagattgcctcagaaaaagaagagattgaacgcctcagagctgag
attgctgaaattcagagtcgccagcagcacggccgaagtgagactgaggagtactcctcc
gagagcgagagcgagagtgaggatgaggaggagctgcagatcattctggaagacttacag
agacagaacgaagagctggaaataaagaacaatcatttgaatcaagcaattcatgaggag
cgcgaggccatcatcgagctgcgcgtgcagctgcggctgctccagatgcagcgagccaag
gccgagcagcaggcgcaggaggacgaggagcctgagtggcgcgggggtgccgtccagccg
cccagagacggcgtccttgagccaaaagcagctaaagagcagccaaaggcaggcaaggag
ccggcaaagccatcgcccagcagggataggaaggagacgtccatcttaatta

Protein Sequence

>RALBP1
MTECFLPPTSSPSEHRRVEHGSGLTRTPSSEEISPTKFPGLYRTGEPSPPHDILHEPPDV
VSDDEKDHGKKKGKFKKKEKRTEGYAAFQEDSSGDEAESPSKMKRSKGIHVFKKPSFSKK
KEKDFKIKEKPKEEKHKEEKHKEEKHKEKKSKDLTAADVVKQWKEKKKKKKPIQEPEVPQ
IDVPNLKPIFGIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKV
DELKAAYDREESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKV
QEFQRLLKELPECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRVLYVF
FTHVQELFGNVVLKQVMKPLRWSNMATMPTLPETQAGIKEEIRRQEFLLNCLHRDLQGGI
KDLSKEERLWEVQRILTALKRKLREAKRQECETKIAQEIASLSKEDVSKEEMNENEEVIN
ILLAQENEILTEQEELLAMEQFLRRQIASEKEEIERLRAEIAEIQSRQQHGRSETEEYSS
ESESESEDEEELQIILEDLQRQNEELEIKNNHLNQAIHEEREAIIELRVQLRLLQMQRAK
AEQQAQEDEEPEWRGGAVQPPRDGVLEPKAAKEQPKAGKEPAKPSPSRDRKETSILI

  • Gold
  • Silver
  • Bronze
  • IntAct