Field Data
UniProt Accession: Q53QZ3
Gene Name: ARHGAP15
Gene Synonim:
GAP/GEF: GAP
Description: Rho GTPase-activating protein 15 (ArhGAP15) (Rho-type GTPase-activating protein 15)
Keywords: 3D-structure;Complete proteome;Cytoplasm;GTPase activation;Membrane;Phosphoprotein;Reference proteome
Entrez ID: 55843
Ensembl Gene ID: ENSG00000075884
Ensembl Protein ID: ENSP00000295095
Our Specificity Rac1
Literature Specificity Rac1
Literature reference
Domain Composition:

Cellular Component

GO ID Description
GO:0005737cytoplasm
GO:0005829cytosol
GO:0016020membrane

Molecular Function

GO ID Description
GO:0005096GTPase activator activity

Biological Process

GO ID Description
GO:0051056regulation of small GTPase mediated signal transduction
GO:0008360regulation of cell shape
GO:0007165signal transduction
GO:0043547positive regulation of GTPase activity

Reactome

Reactome ID Description
R-HSA-194840Rho GTPase cycle

KEGG

Field Data
Localization in this study: cytosolic
Localization in the literature: plasma membrane

Confocal Images

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Cytochalasin D Screen Negative

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organism orgs
Organism: Mus musculus

Nucleotide Sequence

>ARHGAP15
atggagaaaaggacaagctgcagtgtgcagacatctacaaactgtgacaactctctggaa
atactgaattctgcccaccaagctacaggagctgtgcaaatgagaatcaaaaatgccaac
agccaccaagacaggcagagccaaactaaatccatgatcctcaccgatgctgggaaggtc
actgaacctatttcccggcacagaaggaatcattcacagcatgtgttgaaagatgtcatt
ccaccactagaacatccaatggttgaaaaagaagggtatcttcaaaaagccaaaattgca
gatggaggaaagaaactaaggaaaaactggtctacttcctggattgttctttctggtcga
aaaattgaattttacaaagactccaagcagcaagctcttcctaacatgaaaaccaggcac
aacgtggaaagtgtggatttgtgtggtgcacatatagaatgggccaaagaaaaatcaagc
agaaagagtgtctttcagatcacaacagtgtcaggaaatgagttccttctacagtcagat
attgacttcctcatattggattggttccaagctatcaaaaatgcaattgacagattgcca
aagaatccaagttgtgggtccctggagttgttcaatttgcagagatcctcaagttctgaa
ctgccgagtcactgccacatcgatagaaaagaacagaaaccagaacacaggaagtccttc
atgtttcgactgcaccacagtgcttctgatacaagtgacaagaatcgcgtgaagagcaga
ctgaagaagttcatctccagaagaccttctctgaaaactttgcaggaaaagggactcatt
aaagatcaaatttttggctctcatctgcacacagtgtgtgaacgagaacattccacagtt
ccatggtttgtaaagcaatgcattgaagctgttgaaaaaagaggcctagacgttgatgga
atttatcgagttagtggcaatcttgcaacaatacagaagttaagatttattgtcaaccaa
gaagagaagctgaatttggatgacagccagtgggaggacatccacgtcgtcaccggagca
ctgaagatgtttttccgggagctgtctgaaccgctcttcccttacagtttctttgagcgg
tttgtggaggcgatcaaaaaacaagacagcaatgaaaaaattgaaactatgaggtctctg
gtaaaacgtctccctccaccaaatcatgataccatgaaaatcctcttcagacatctaacc
aagatagtggccaaagcctcccagaatctcatgtccacccaaagcttggggattgtgttt
ggacccacccttctgcgagcggaaaatgagtcagggaatgtagcggtccacatggtatac
caaaaccagatagcagagttcatgctgactgagtacgataagatcttcagctcagaggaa
gacttaatta

Protein Sequence

>ARHGAP15
MEKRTSCSVQTSTNCDNSLEILNSAHQATGAVQMRIKNANSHQDRQSQTKSMILTDAGKV
TEPISRHRRNHSQHVLKDVIPPLEHPMVEKEGYLQKAKIADGGKKLRKNWSTSWIVLSGR
KIEFYKDSKQQALPNMKTRHNVESVDLCGAHIEWAKEKSSRKSVFQITTVSGNEFLLQSD
IDFLILDWFQAIKNAIDRLPKNPSCGSLELFNLQRSSSSELPSHCHIDRKEQKPEHRKSF
MFRLHHSASDTSDKNRVKSRLKKFISRRPSLKTLQEKGLIKDQIFGSHLHTVCEREHSTV
PWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGA
LKMFFRELSEPLFPYSFFERFVEAIKKQDSNEKIETMRSLVKRLPPPNHDTMKILFRHLT
KIVAKASQNLMSTQSLGIVFGPTLLRAENESGNVAVHMVYQNQIAEFMLTEYDKIFSSEE
DLI

  • Gold
  • Silver
  • Bronze
  • IntAct