Field Data
UniProt Accession: Q5TG30
Gene Name: ARHGAP40
Gene Synonim: C20orf95
GAP/GEF: GAP
Description: Rho GTPase-activating protein 40 (Rho-type GTPase-activating protein 40)
Keywords: Complete proteome;GTPase activation;Polymorphism;Reference proteome
Entrez ID: None
Ensembl Gene ID: ENSG00000124143
Ensembl Protein ID: ENSP00000362442
Our Specificity Cdc42, RhoA
Literature Specificity None
Domain Composition:

Cellular Component

GO ID Description
GO:0005829cytosol

Molecular Function

GO ID Description
GO:0005096GTPase activator activity

Biological Process

GO ID Description
GO:0051056regulation of small GTPase mediated signal transduction
GO:0007165signal transduction
GO:0043547positive regulation of GTPase activity

Reactome

Reactome ID Description
R-HSA-194840Rho GTPase cycle

KEGG

Field Data
Localization in this study: cytosolic
Localization in the literature:

Confocal Images

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Cytochalasin D Screen Negative

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organism orgs
Organism: Homo sapiens

Nucleotide Sequence

>ARHGAP40
atggatcagcttccccagaagaatctcctgcgactacaccctgctggctctgctggctgt
tccactggagtggagagctccagcatggatggcttttggatggaggtggaacagatccaa
cagagagatgagctgagggaagaggacagtggcgggaatgaaggccagcttccagaggaa
ggggaagctgaatcccagtggctgcaggacacaggcctgtcgggcctccttggtggcctg
ggcttggatggtgatcaccaggagctcctgtccaccctgacacagacccaggtggccgct
gtgtgccgccggctggacatctatgctcgctcagtgcgaagacaacacaagacacctgtc
agagatgtcagggatgtctttggggtcttcaattcagggaaaatgtcgtcagagaatggc
gactccggtatgaagggggcccagctcagttccggggcctctaagtttcctccagcagca
gagcctggggggctgcaggagcaggctgggagggaagaagccttcaacatggactctgcc
tactcagaacaagctgcggtgctcctgcagaggagcaggccatcccggggaggcacctct
gcctggggcaagtgttccctgccgaagtttaccgtccccaaaggcagacttggcgtgacg
aggataggagacttgtccctgcaggatatgaggaaggtaccttctctggccctcatagag
ctgaccgcgctctgtgacatcctcggcttggacctgaagaggagcaaggcggggaagtgg
aaagcggcagaaactcgcctctttggtgtgccccttgacagcctgctagaagctgaccac
aaagtcctccccagcacacaggtcccgctggtccttcaagccctgctgtcctgtttggaa
aagagaggactggacatggaaggcattctcagggtgcccggatcccaggccagggtcaag
gggctggaacagaaactggagagagacttctatgctggcctttttagctgggacgaggtt
catcacaatgacgcctctgatttgctcaaaaggttcatccggaagctgccgacacctttg
ctcacggctgagtacctcccggccttcgccgtggtgcctaacatccccaacctgaagcag
cgcctgcaggttcttcacctgctcatcctcatcctcccagaacccaacagaaatgcctta
aaggcactgctggaattcctcaggaaggtggtggcccgggaacagcacaacaagatgact
ctgaggaatgtttccaccgtgatggcccctaacctctttctgcaccaagggcggcccccc
aagctccccaaaggcaaggagaagcagctggcagaaggggcagccgaggtggtgcagata
atggtgcactaccaggatctgctgtggacggtcgcctctttcctggtcgcccaggtgcga
aaactgaacgacagtagcagcaggcgcccccagctctgcgacgcaggcctcaagacttgg
ctgcggaggatgcacgcagacagggacaaggcgggggacggcctcgaggcgactcccaag
gtggcaaagatccaggtggtctggcctatcaaggaccccttgaaggtgcctctcaccccc
agcaccaaagtggcccacgtcctgaggcagttcacagagcacctcagccctggttccaag
ggtcaagaagacagtgaggacatggacagcctccttctacaccataggtccatggagtca
gccaacatcctcctctatgaagttggagggaatatcaatgagcatcgcctggacccagat
gcctacctcttagatctgtaccgtgccaacccgcatggtccttttggcttttgggaggcg
gagactgagactggagtccagaggaccaaggaggacgaggtaactgccgtggtccaggtg
ggagaaaatgtcgagacccgggtaattgcggctgagctgtccgaggtgctgacggctggg
cgagaggagcggttgaatgtatgcacaacgcccagagggactgctattggcaaagtgatg
gccccacagggaccaaatgtgaagctaaagcaggatacgcaggtcggagataaggccaag
aacagattccctttagcgctcaagtgctgtttgtcagaaattgacagccccacggccctg
gccggaatgtactgcatgaataaagacccctctgtggtgggacccagctgcccgaaggtc
agcccctgtgaattaatta

Protein Sequence

>ARHGAP40
MDQLPQKNLLRLHPAGSAGCSTGVESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEE
GEAESQWLQDTGLSGLLGGLGLDGDHQELLSTLTQTQVAAVCRRLDIYARSVRRQHKTPV
RDVRDVFGVFNSGKMSSENGDSGMKGAQLSSGASKFPPAAEPGGLQEQAGREEAFNMDSA
YSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIE
LTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLE
KRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPL
LTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMT
LRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVR
KLNDSSSRRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKIQVVWPIKDPLKVPLTP
STKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPD
AYLLDLYRANPHGPFGFWEAETETGVQRTKEDEVTAVVQVGENVETRVIAAELSEVLTAG
REERLNVCTTPRGTAIGKVMAPQGPNVKLKQDTQVGDKAKNRFPLALKCCLSEIDSPTAL
AGMYCMNKDPSVVGPSCPKVSPCELI

  • Gold
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  • IntAct