Field Data
UniProt Accession: Q6ZR37
Gene Name: PLEKHG7
Gene Synonim:
GAP/GEF: GEF
Description: Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7)
Keywords: Complete proteome;Polymorphism;Reference proteome
Entrez ID: 440107
Ensembl Gene ID: ENSG00000187510
Ensembl Protein ID: ENSP00000492692
Our Specificity
Literature Specificity None
Domain Composition:

Cellular Component

Molecular Function

GO ID Description
GO:0005089Rho guanyl-nucleotide exchange factor activity

Biological Process

GO ID Description
GO:0043547positive regulation of GTPase activity
GO:0035023regulation of Rho protein signal transduction

Reactome

KEGG

Field Data
Localization in this study: vesicles
Localization in the literature:

Confocal Images

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Cytochalasin D Screen Negative

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organism orgs
Organism: Homo sapiens

Nucleotide Sequence

>PLEKHG7
atgatctttatgaatacactaagatatctgcaaactcatgaatatctcctagatgtggat
ttatggagactttttgcaaacctggaggagttaactcagacaagccttggttttgtgaac
agtctctttggcatcatcaaggactatgtagacgcttctgagatttcctcatcactggat
tttatttccgtgctcacaaagtatttccgagggagtctctgtcagagccaccagacctac
tgcctgaactattcagctgctatcttttatcttgagagcctgaggcagagagatgacttt
ggaatttatttaaaatggtgtgagcagaatgaacaatgcagacggctccacgtgccagag
ctgctagtggccccactacagaggctcactcgatatccgttgttgctgaagaatatctgg
aaaaggagcatggactctgctgagaaaatcatgatctactccatcaaggaaaaggtggaa
aagtccatccgggaccttgaaggaaaagtgaagtggctggacaatttccaaaaatttaga
tatctacaggagattatagtgtggccaccgctttgggatagagataaaaggtttttcatt
ccagagtgtttgaaacacatttttaaagaacacatggcagaaaacatcttgtcaccaacc
agcagacaccttctctatgaaggaaaattaactcttgcagaaagcacaagattcctagat
gtttatctgtttctcttcaatgatttcctcttagttacgaaaactaagtgcaacaaaaag
aaacttggaggctcagaccctggtttaatgtgtccttctcttactcctgagttgcaagca
gtaataaaagagggtggttcgtgtacagtactcgatcagcctattccactagatagattg
gtagtcaaaagtattgaaccactccatgtgtcagtctttgggctgagaaatgcttttctt
atacaacacgaaaacagatatcgacagtgtatagcagcattcttattacaagcccaaacg
gaaaacatcaaaaaaacatggatggcacaaataacaactgcaatttcttgctttaccaag
agtcaggaaaccaagaaaatatctttattcacattgcccgcagaatcctctgaaatttta
atta

Protein Sequence

>PLEKHG7
MIFMNTLRYLQTHEYLLDVDLWRLFANLEELTQTSLGFVNSLFGIIKDYVDASEISSSLD
FISVLTKYFRGSLCQSHQTYCLNYSAAIFYLESLRQRDDFGIYLKWCEQNEQCRRLHVPE
LLVAPLQRLTRYPLLLKNIWKRSMDSAEKIMIYSIKEKVEKSIRDLEGKVKWLDNFQKFR
YLQEIIVWPPLWDRDKRFFIPECLKHIFKEHMAENILSPTSRHLLYEGKLTLAESTRFLD
VYLFLFNDFLLVTKTKCNKKKLGGSDPGLMCPSLTPELQAVIKEGGSCTVLDQPIPLDRL
VVKSIEPLHVSVFGLRNAFLIQHENRYRQCIAAFLLQAQTENIKKTWMAQITTAISCFTK
SQETKKISLFTLPAESSEILI

  • Gold
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  • Bronze
  • IntAct