Field Data
UniProt Accession: Q6ZRI8
Gene Name: ARHGAP36
Gene Synonim:
GAP/GEF: GAP
Description: Rho GTPase-activating protein 36
Keywords: Alternative splicing;Complete proteome;GTPase activation;Reference proteome;Signal
Entrez ID: 158763
Ensembl Gene ID: ENSG00000147256
Ensembl Protein ID: ENSP00000492307
Our Specificity
Literature Specificity None
Domain Composition:

Cellular Component

GO ID Description
GO:0005829cytosol

Molecular Function

GO ID Description
GO:0005096GTPase activator activity

Biological Process

GO ID Description
GO:0051056regulation of small GTPase mediated signal transduction
GO:0007165signal transduction
GO:0043547positive regulation of GTPase activity

Reactome

Reactome ID Description
R-HSA-194840Rho GTPase cycle

KEGG

Field Data
Localization in this study: lysosomes, plasma_membrane, vesicles
Localization in the literature: plasma membrane, vesicles

Confocal Images

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Cytochalasin D Screen Negative

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organism orgs
Organism: Homo sapiens

Nucleotide Sequence

>ARHGAP36
atgagtgtcttgggaggagccccaggacacaaccccgaccgcaggacgaagatggtatcg
atacacagcctctctgagctggagcgtctgaagctgcaagagactgcttaccacgaactc
gtggccagacatttcctctccgaattcaaacctgacagagctctgcctattgaccgtccg
aacaccttggataagtggtttctgattttgagaggacagcagagggctgtatcacacaag
acatttggcattagcctggaagaggtcctggtgaacgagtttacccgccgcaagcatctt
gaactgacagccacgatgcaggttgaagaagccaccggtcaggctgcgggccgtcgtcgg
ggaaacgtggtgcgaagggtgtttggccgcatccggcgctttttcagtcgcaggcggaat
gagcccaccttgccccgggagttcactcgccgtgggcgtcgaggtgcagtgtctgtggat
agtctggctgagctggaagacggagccctgctgctgcagaccctgcagctttcaaaaatt
tcctttccaattggccaacgacttctgggatccaaaaggaagatgagtctcaatccgatt
gcgaaacaaatcccccaggttgttgaggcttgctgccaattcattgaaaaacatggctta
agcgcagtggggatttttacccttgaatactccgtgcagcgagtgcgtcagctccgtgaa
gaatttgatcaaggtctggatgtagtgctggatgacaatcagaatgtgcatgatgtggct
gcactcctcaaggagtttttccgtgacatgaaggattctctgctgccagatgatctgtac
atgtcattcctcctgacagcaactttaaagccccaggatcagctttctgccctgcagttg
ctggtctacctgatgccaccctgccacagtgataccctggagcgtctgctgaaggccctg
cataaaatcactgagaactgcgaggactcaattggcattgatggacagttggtcccaggc
aaccgtatgacttccactaacttggccttggtgtttggatctgctctcctgaaaaaagga
aagtttggcaagagagagtccaggaaaacaaagctggggattgatcactatgttgcttct
gtcaatgtggtccgtgccatgattgataactgggatgtcctcttccaggtgcctccccat
attcagaggcaggttgctaagcgcgtgtggaagtccagcccggaagcacttgattttatc
agacgcaggaacttgaggaagatccagagtgcacgcataaagatggaagaggatgcacta
ctttctgatccagtggaaacctctgctgaagcccgggctgctgtccttgctcaaagcaag
ccttctgatgaaggttcctctgaggagccagctgtgccttccggcactgcccgttcccat
gacgatgaggaaggagcgggtaaccctcccattccggagcaagaccgcccattgctccgt
gtgccccgggagaaggaggccaaaactggcgtcagctacttctttcctt

Protein Sequence

>ARHGAP36
MSVLGGAPGHNPDRRTKMVSIHSLSELERLKLQETAYHELVARHFLSEFKPDRALPIDRP
NTLDKWFLILRGQQRAVSHKTFGISLEEVLVNEFTRRKHLELTATMQVEEATGQAAGRRR
GNVVRRVFGRIRRFFSRRRNEPTLPREFTRRGRRGAVSVDSLAELEDGALLLQTLQLSKI
SFPIGQRLLGSKRKMSLNPIAKQIPQVVEACCQFIEKHGLSAVGIFTLEYSVQRVRQLRE
EFDQGLDVVLDDNQNVHDVAALLKEFFRDMKDSLLPDDLYMSFLLTATLKPQDQLSALQL
LVYLMPPCHSDTLERLLKALHKITENCEDSIGIDGQLVPGNRMTSTNLALVFGSALLKKG
KFGKRESRKTKLGIDHYVASVNVVRAMIDNWDVLFQVPPHIQRQVAKRVWKSSPEALDFI
RRRNLRKIQSARIKMEEDALLSDPVETSAEARAAVLAQSKPSDEGSSEEPAVPSGTARSH
DDEEGAGNPPIPEQDRPLLRVPREKEAKTGVSYFFP

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