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Cellular Component

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GO ID	Description
GO:0005737	cytoplasm
GO:0070062	extracellular exosome
GO:0030027	lamellipodium
GO:0005829	cytosol
GO:0016020	membrane
GO:0030426	growth cone
GO:0030175	filopodium
GO:0042995	cell projection

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Molecular Function

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GO ID	Description
GO:0005089	Rho guanyl-nucleotide exchange factor activity
GO:0005057	signal transducer activity, downstream of receptor
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0005096	GTPase activator activity

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Biological Process

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GO ID	Description
GO:0051056	regulation of small GTPase mediated signal transduction
GO:0043547	positive regulation of GTPase activity
GO:0019216	regulation of lipid metabolic process
GO:0043065	positive regulation of apoptotic process
GO:0007165	signal transduction
GO:0035023	regulation of Rho protein signal transduction
GO:0035556	intracellular signal transduction

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Reactome

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Reactome ID	Description
R-HSA-1989781	PPARA activates gene expression
R-HSA-416482	G alpha (12/13) signalling events
R-HSA-194840	Rho GTPase cycle
R-HSA-193648	NRAGE signals death through JNK

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KEGG

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Field	Data
Localization in this study:	nuclear_membrane, plasma_membrane
Localization in the literature:	plasma membrane