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Cellular Component

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GO ID	Description
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0042995	cell projection
GO:0002102	podosome
GO:0031982	vesicle
GO:0031410	cytoplasmic vesicle
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0032587	ruffle membrane
GO:0043234	protein complex
GO:0043198	dendritic shaft
GO:0005819	spindle
GO:0014069	postsynaptic density
GO:0005886	plasma membrane
GO:0043025	neuronal cell body
GO:0016020	membrane
GO:0005925	focal adhesion
GO:0005874	microtubule
GO:0005923	bicellular tight junction
GO:0030054	cell junction

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Molecular Function

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GO ID	Description
GO:0005089	Rho guanyl-nucleotide exchange factor activity
GO:0030676	Rac guanyl-nucleotide exchange factor activity
GO:0008017	microtubule binding
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0017048	Rho GTPase binding
GO:0048365	Rac GTPase binding
GO:0008270	zinc ion binding
GO:0005515	protein binding
GO:0046872	metal ion binding
GO:0008134	transcription factor binding

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Biological Process

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GO ID	Description
GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0043547	positive regulation of GTPase activity
GO:0071225	cellular response to muramyl dipeptide
GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
GO:0035023	regulation of Rho protein signal transduction
GO:0035556	intracellular signal transduction
GO:0051301	cell division
GO:0071802	negative regulation of podosome assembly
GO:0000902	cell morphogenesis
GO:0007026	negative regulation of microtubule depolymerization
GO:0071356	cellular response to tumor necrosis factor
GO:0006886	intracellular protein transport
GO:0050768	negative regulation of neurogenesis
GO:0071474	cellular hyperosmotic response
GO:0043065	positive regulation of apoptotic process
GO:0007049	cell cycle
GO:0042127	regulation of cell proliferation
GO:0051056	regulation of small GTPase mediated signal transduction
GO:0032760	positive regulation of tumor necrosis factor production
GO:0060546	negative regulation of necroptotic process
GO:0045087	innate immune response
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0007015	actin filament organization
GO:0000132	establishment of mitotic spindle orientation
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0002376	immune system process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0032755	positive regulation of interleukin-6 production

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Reactome

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Reactome ID	Description
R-HSA-416482	G alpha (12/13) signalling events
R-HSA-194840	Rho GTPase cycle
R-HSA-193648	NRAGE signals death through JNK

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KEGG

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Kegg ID	Description
hsa04530	Tight junction
hsa05418	Fluid shear stress and atherosclerosis
hsa05130	Pathogenic Escherichia coli infection

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Field	Data
Localization in this study:	tubulin
Localization in the literature:	tubulin plasma membrane (junctions)