---

Cellular Component

---

GO ID	Description
GO:0005829	cytosol

---

Molecular Function

---

GO ID	Description
GO:0005089	Rho guanyl-nucleotide exchange factor activity
GO:0005085	guanyl-nucleotide exchange factor activity

---

Biological Process

---

GO ID	Description
GO:0043065	positive regulation of apoptotic process
GO:0051056	regulation of small GTPase mediated signal transduction
GO:0043547	positive regulation of GTPase activity
GO:0030036	actin cytoskeleton organization
GO:0035023	regulation of Rho protein signal transduction

---

Reactome

---

Reactome ID	Description
R-HSA-416482	G alpha (12/13) signalling events
R-HSA-194840	Rho GTPase cycle
R-HSA-193648	NRAGE signals death through JNK

---

KEGG

---

---

Field	Data
Localization in this study:	actin, plasma_membrane, vesicles
Localization in the literature:	actin plasma membrane (junctions)