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Cellular Component

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GO ID	Description
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0015629	actin cytoskeleton
GO:0036064	ciliary basal body
GO:0005634	nucleus
GO:0016020	membrane
GO:0005886	plasma membrane
GO:0042995	cell projection
GO:0005829	cytosol

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Molecular Function

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GO ID	Description
GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0005543	phospholipid binding
GO:0003924	GTPase activity
GO:0003714	transcription corepressor activity
GO:0005096	GTPase activator activity
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003677	DNA binding
GO:0005525	GTP binding

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Biological Process

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GO ID	Description
GO:0035024	negative regulation of Rho protein signal transduction
GO:0007165	signal transduction
GO:0007411	axon guidance
GO:0007413	axonal fasciculation
GO:0043547	positive regulation of GTPase activity
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0021955	central nervous system neuron axonogenesis
GO:0001843	neural tube closure
GO:0016477	cell migration
GO:0030879	mammary gland development
GO:0051056	regulation of small GTPase mediated signal transduction
GO:0045724	positive regulation of cilium assembly
GO:0008360	regulation of cell shape
GO:0045892	negative regulation of transcription, DNA-templated
GO:0010976	positive regulation of neuron projection development
GO:0032956	regulation of actin cytoskeleton organization
GO:0097485	neuron projection guidance
GO:0008064	regulation of actin polymerization or depolymerization
GO:0031668	cellular response to extracellular stimulus
GO:0050770	regulation of axonogenesis
GO:0030950	establishment or maintenance of actin cytoskeleton polarity
GO:0044319	wound healing, spreading of cells
GO:0006355	regulation of transcription, DNA-templated
GO:0030900	forebrain development
GO:0006351	transcription, DNA-templated
GO:0043010	camera-type eye development
GO:0043116	negative regulation of vascular permeability

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Reactome

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Reactome ID	Description
R-HSA-8849471	PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
R-HSA-416550	Sema4D mediated inhibition of cell attachment and migration
R-HSA-194840	Rho GTPase cycle

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KEGG

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Kegg ID	Description
hsa04670	Leukocyte transendothelial migration
hsa04611	Platelet activation
hsa04510	Focal adhesion
hsa04810	Regulation of actin cytoskeleton

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Field	Data
Localization in this study:	actin, focal_adhesions
Localization in the literature:	focal adhesions cytosolic invadopodia