Field Data
UniProt Accession: Q9NYF5
Gene Name: FAM13B
Gene Synonim: C5orf5, FAM13B1
GAP/GEF: GAP
Description: Protein FAM13B (GAP-like protein N61)
Keywords: Alternative splicing;Complete proteome;GTPase activation;Polymorphism;Reference proteome
Entrez ID: 51306
Ensembl Gene ID: ENSG00000031003
Ensembl Protein ID: ENSP00000394669
Our Specificity Cdc42, Rac1
Literature Specificity None
Domain Composition:

Cellular Component

GO ID Description
GO:0005829cytosol

Molecular Function

GO ID Description
GO:0005096GTPase activator activity

Biological Process

GO ID Description
GO:0051056regulation of small GTPase mediated signal transduction
GO:0007165signal transduction
GO:0043547positive regulation of GTPase activity

Reactome

Reactome ID Description
R-HSA-194840Rho GTPase cycle

KEGG

Field Data
Localization in this study: cytosolic
Localization in the literature:

Confocal Images

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Cytochalasin D Screen Negative

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organism orgs
Organism: Homo sapiens

Nucleotide Sequence

>FAM13B
atgaggaagagctcctccccttccttgagtaactgcaactccgttcttgctaacaaaata
tttggaattccacttgatgagctgcagcagggaggacatccagacaatgaggttccattc
atagtccgccacgttgtggactatattgaggaacatggaggtctggagcaacaaggactt
tttcaagtcaatggaaatgctgagacagtggagtggcttcggcagagatacgacagcgga
gaagaggtggatttggttaaggaagcagatgttccctcagctattagccttcttagattt
tttcttcaagaacttcctgaacctgttatccctggcagtttacatattcacttgatgcag
ctttctcaagattataataatgaagatgaatttggaagaaagttgaggttcctcttgcaa
cagcttccacctgttaattatagtttgttaaagtttctgtgtagatttttagccaatgta
gcatcacatcatgaagaaatttggtctgcaaattctttggctgctgtctttggtccagat
gtcttccacatttacacagatgtggaagacatgaaagagcaagaaatagtgagcaggata
atggctggacttctggaaaactactatgagttttttgagaatgaagaggaagatttttca
tctaatgatttgagttcaattactgaacaggttaatgaactttctgaggaagaagaggaa
gatgaaaagctggaacatattgaagaacttccagaagagggtgcagaaaaatcaaatgac
atgccagaggtggtacaattaaggatgactgaaaacatcctggaatcaaatagtgttacg
gcaacaagcacccatatatctcccatcagcatcctaccagcctctacagatattttagaa
agaacaattagagcagctgtggaacagcacctttttgatcttcagagcagcatagatcat
gatcttaagaatttacaacagcaaagtgtggtgtgtaataatgaagcagaaagtattcat
tgtgatggggaaggatctaataaccagattgatattgctgatgatattattaatgccagt
gaaagtaacagagactgttcaaaacctgtggctagcactaatttagacaatgaagctatg
cagcaagattgtgtatttgagaatgaagaaaatacccagtctgtaggtatattgttagag
ccatgcagtgaccgtggtgatagtgaagatggctgtcttgagagggaagaatatttgtta
tttgacagtgataaattgtcacacttgattctggattctagtagcaagatatgtgatttg
aatgccaacactgaatcagaagtaccaggaggtcagagtgttggtgttcaaggggaagca
gcgtgtgtcagtattccacatttagatctgaagaatgtttctgatggtgataaatgggaa
gagccatttcctgcttttaagtcttggcaggaggactctgagtctggagaagctcagctg
tctccacaagctggaagaatgaatcatcaccccttggaagaggactgtcctccagtatta
tcacaccgcagtttagattttggtcaaagccagcgtttcctacatgatccagaaaagttg
gattcctcatctaaagcactgtcttttactagaattcgaagatcatcctttagttcaaaa
gatgaaaagagagaggacagaacaccttatcagctggtcaagaaacttcagaagaaaatc
agacaatttgaggaacagtttgaaagggaaagaaatagcaagccctcctacagtgatatt
gctgccaatccaaaggtattaaaatggatgacagagcttacaaaactgcggaagcaaatt
aaagatgcaaaacacaaaaattctgatggagaatttgtacctcagacacgtccacgtagt
aacacacttccaaaaagctttggctcttctctagaccatgaagatgaagagaatgaagat
gaacccaaggtcattcagaaggagaaaaaaccatctaaagaagcaacccttgaacttatt
cttaaaagactgaaagaaaaacgtattgagaggtgtcttccagaagatatcaagaaaatg
accaaagatcatttggtagaagagaaagcttctcttcagaaaagtcttctttactatgaa
agtcaacatggaaggccggtgaccaaggaagaaaggcacattgttaaacctctctatgat
agatacaggcttgtaaaacaaatgctgacaagagctagcatcactcctgtccttggatct
ccatccaccaagcgaaggggtcagatgttacagccaatcatagaaggagaaactgcacat
ttttttgaagaaatcaaggaggaagaagaagatggtgttaatctgtcctctgagttaggt
gatatgttgaaaactgcagtacaggtacagtcttcattagaaaactctgaatctgatgtt
gaagaaaatcaagaaaaactggctctggatctccgattgtcaagttctcgagcagcttct
atgcctgaattattggaacaactttggaaagccagagctgaaaaaaagaaactacgcaaa
acgttgcgggaatttgaagaagcattttatcaacaaaatggaaggaatgcccagaaagag
gatcgtgttccagtgcttgaggagtacagagagtacaagaaaattaaagccaagcttagg
cttcttgaagttcttataagcaaacaagattcttcaaaatccatat

Protein Sequence

>FAM13B
MRKSSSPSLSNCNSVLANKIFGIPLDELQQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGL
FQVNGNAETVEWLRQRYDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQ
LSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFGPD
VFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEE
DEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDILE
RTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIINAS
ESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEYLL
FDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDKWE
EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKL
DSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDI
AANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENED
EPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKKMTKDHLVEEKASLQKSLLYYE
SQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAH
FFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAAS
MPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLR
LLEVLISKQDSSKSI

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  • IntAct