Field Data
UniProt Accession: Q9P2N2
Gene Name: ARHGAP28
Gene Synonim: KIAA1314
GAP/GEF: GAP
Description: Rho GTPase-activating protein 28 (Rho-type GTPase-activating protein 28)
Keywords: Alternative splicing;Complete proteome;GTPase activation;Phosphoprotein;Polymorphism;Reference proteome
Entrez ID: None
Ensembl Gene ID: ENSG00000088756
Ensembl Protein ID: ENSP00000435990
Our Specificity RhoA
Literature Specificity RhoA
Literature reference
Domain Composition:

Cellular Component

GO ID Description
GO:0005829cytosol

Molecular Function

GO ID Description
GO:0005096GTPase activator activity

Biological Process

GO ID Description
GO:0051497negative regulation of stress fiber assembly
GO:0051056regulation of small GTPase mediated signal transduction
GO:1904425negative regulation of GTP binding
GO:0007165signal transduction
GO:0043547positive regulation of GTPase activity

Reactome

Reactome ID Description
R-HSA-194840Rho GTPase cycle

KEGG

Field Data
Localization in this study: actin
Localization in the literature:

Confocal Images

Card image cap
organism orgs
Organism: Mus musculus

Nucleotide Sequence

>ARHGAP28
atggaggtggaggactcgggcggcgtggtgctgaccgcctaccactcgcacgcgcgctcg
caaccgcagggcgctgagccacgctgcgcgtcccgggccagccatccgctcagcagaaaa
tccattcctcgctgccgacgaatcaacaggatgctctccaatgaatccctgcatcctccc
tcctttagtcgctccaactctcaagcctcagtagacagcagcgcatccatggaggagttc
ctgcgggaaattgagagtatcaaagagagcagcgtgggggcgtcgcaggagcagccaccc
actgctgctgctgctgctgctgaagtcaagccagtggatgaaggagagcttgaagcggag
tggctacaagatgtgggattgtcaactctgatctctggcaacgaagaggaagacggtaaa
gcgctcctgtctacattgactcggacccaagctgctgcagtgaaaaagagatacaacaca
tatactcagactctgaggaaaaagaataaacaacccgtcagggatgtcagagacatcttc
ggagtcagcgaatctcctcctagtgattcttgtgagcatgctactcagttggacggtacc
aaggaagaaaaagatctgccaggagttaccaagacaagcagacctctgccagacgatgct
tctctcagtagtaccaccctatccaatggcgcccaggatgaagaaggtggttttgtggcc
ctacagagtggttctgtgtcaatacttgaggctatcccggatattgctgttcgcaccaat
ggatctgcagatgctgagcagtcggttcagagcacattgagtgatgatgattatcacggg
aagaacgttccagcagaggctgaagagctgtcctttgaggtctcttactcagaaatggtg
acagaaatgcctgatagaaataaatggaagaagtcggacattaagaaagaagactatgtc
ttaactaaatttatcattcagaaaacaagatttgggttggccgagacgggggacctgtct
gtggaagacatgaagaaaatccgccacctctctctgattgagctgacagccttcttcgat
acttttgggatacaactgaagagaaacaaaaccgagcgagtgagaggccgagacaacggg
attttcggagtgccacttacagtcctcctggacaatgaccggaagaaggaccctgcagtg
aaagttcccctggtgttacaaaaattttttcagaaagtcgaggaatcaggtctggaatcg
gaaggaatttttcgactctcgggatgtactgccaaagtcaagcagtaccgcgaagaactg
gatgccaggttcaatgctgacaagttcaagtgggacaagatgtgtcacagagaagctgcg
gtcatgttgaaagcattcttcagagagctgcccacctctctcttccctgttgaatatata
cccgccttcatctctctgatggaaagaggacctgacatcaaagtgcagtttcaagccttg
cacctcatggtcatggccctgcctgatgccaacagggacacagcgcaggctctgatggca
ttcttcaataaagtgatcgccaacgaatccaagaaccgcatgaacctgtggaacatttcc
acagtgatggcgcccaacttgttcttcagcagaagcaagcactctgactgcgaggaactg
ctgctggccaacacggcgacccacatcatccgcctgatgctgaagtaccagaagattctg
tggaaggttccatctttcttgatcacccaggtcagaaggatgaatgaggccaccatgctg
ttgaagaagcagctcccgagtatgaagaagctgctcaggaggaagaccctggatcgagag
gtttcaatcctcaagacctcaaaggtaccacaaaaatcaccttcctcaagaagaatgtct
gatgtgccagaaggtgtcataagggtccacgctccacttctgtccaaagtgtccatggcc
attcagctcaacagtcagaccaaagccaaagatgtcctggcgaaatttcagtataagaac
ccactagcaaccaaacatgtacttcgggggtttctgtgtgtccctgtgcttgaccggttt
ctagattgcccagtgggccagttaatta

Protein Sequence

>ARHGAP28
MEVEDSGGVVLTAYHSHARSQPQGAEPRCASRASHPLSRKSIPRCRRINRMLSNESLHPP
SFSRSNSQASVDSSASMEEFLREIESIKESSVGASQEQPPTAAAAAAEVKPVDEGELEAE
WLQDVGLSTLISGNEEEDGKALLSTLTRTQAAAVKKRYNTYTQTLRKKNKQPVRDVRDIF
GVSESPPSDSCEHATQLDGTKEEKDLPGVTKTSRPLPDDASLSSTTLSNGAQDEEGGFVA
LQSGSVSILEAIPDIAVRTNGSADAEQSVQSTLSDDDYHGKNVPAEAEELSFEVSYSEMV
TEMPDRNKWKKSDIKKEDYVLTKFIIQKTRFGLAETGDLSVEDMKKIRHLSLIELTAFFD
TFGIQLKRNKTERVRGRDNGIFGVPLTVLLDNDRKKDPAVKVPLVLQKFFQKVEESGLES
EGIFRLSGCTAKVKQYREELDARFNADKFKWDKMCHREAAVMLKAFFRELPTSLFPVEYI
PAFISLMERGPDIKVQFQALHLMVMALPDANRDTAQALMAFFNKVIANESKNRMNLWNIS
TVMAPNLFFSRSKHSDCEELLLANTATHIIRLMLKYQKILWKVPSFLITQVRRMNEATML
LKKQLPSMKKLLRRKTLDREVSILKTSKVPQKSPSSRRMSDVPEGVIRVHAPLLSKVSMA
IQLNSQTKAKDVLAKFQYKNPLATKHVLRGFLCVPVLDRFLDCPVGQLI

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