UniProt AccessionGene_NameGene_Name SynonymGAP GEF RhoA Rac1 Cdc42 keywords localization
Q12979ABRYesYesNoYesNoAlternative splicing, Complete proteome, GTPase activation, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteomecytosolic
Q12802AKAP13BRX, HT31, LBCNoYesYesNoNo3D-structure, Alternative splicing, Coiled coil, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Membrane, Metal-binding, Methylation, Nucleus, Phosphoprotein, Polymorphism, Proto-oncogene, Reference proteome, Zinc, Zinc-fingercytosolic
Q96Q42ALS2ALS2CR6, KIAA1563NoYesNoNoNoAcetylation, Alternative splicing, Amyotrophic lateral sclerosis, Complete proteome, Guanine-nucleotide releasing factor, Neurodegeneration, Phosphoprotein, Polymorphism, Reference proteome, Repeatvesicles
Q96P48ARAP1YesNoNoYesYes3D-structure, Alternative splicing, Cell membrane, Complete proteome, Cytoplasm, GTPase activation, Golgi apparatus, Membrane, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Zinc, Zinc-fingercytosolic
Q8WZ64ARAP2CENTD1, KIAA0580YesNoYesYesYes3D-structure, Complete proteome, Cytoplasm, GTPase activation, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Zinc, Zinc-fingeractin, focal adhesions
Q8WWN8ARAP3CENTD3YesNoNoYesYes3D-structure, Alternative splicing, Cell membrane, Cell projection, Complete proteome, Cytoplasm, Cytoskeleton, GTPase activation, Membrane, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Zinc, Zinc-fingeractin
Q07960ARHGAP1CDC42GAP, RHOGAP1YesNoYesNoYes3D-structure, Acetylation, Complete proteome, Cytoplasm, Direct protein sequencing, GTPase activation, Phosphoprotein, Polymorphism, Reference proteome, SH3-bindingvesicles
P98171ARHGAP4KIAA0131, RGC1, RHOGAP4YesNoNoYesNo3D-structure, Alternative splicing, Coiled coil, Complete proteome, Cytoplasm, GTPase activation, Phosphoprotein, Polymorphism, Reference proteome, SH3 domaincytosolic
Q13017ARHGAP5RHOGAP5YesNoYesNoNo3D-structure, Alternative splicing, Cell membrane, Complete proteome, Cytoplasm, GTPase activation, Membrane, Nitration, Phosphoprotein, Polymorphism, Reference proteome, Repeatactin
O43182ARHGAP6RHOGAP6YesNoYesNoNoAlternative splicing, Complete proteome, Cytoplasm, GTPase activation, Phosphoprotein, Polymorphism, Reference proteome, SH3-bindingcytosolic
P85298ARHGAP8YesNoYesNoNoAlternative splicing, Complete proteome, GTPase activation, Polymorphism, Reference proteomecytosolic
Q9BRR9ARHGAP9YesNoNoYesNo3D-structure, Alternative splicing, Complete proteome, GTPase activation, Lipid-binding, Phosphoprotein, Polymorphism, Reference proteome, SH3 domainactin, focal adhesions, mitochondria, plasma membrane
A1A4S6ARHGAP10YesNoYesNoNo3D-structure, Cell membrane, Complete proteome, Cytoplasm, GTPase activation, Membrane, Phosphoprotein, Polymorphism, Reference proteome, SH3 domaincytosolic
Q6P4F7ARHGAP11AKIAA0013YesNoYesNoNo3D-structure, Alternative splicing, Complete proteome, GTPase activation, Phosphoprotein, Polymorphism, Reference proteomeactin, nucleus
Q3KRB8ARHGAP11BFAM7B1YesNoYesNoYesComplete proteome, Reference proteomemitochondria
Q8IWW6ARHGAP12YesNoNoYesNoAlternative splicing, Complete proteome, GTPase activation, Phosphoprotein, Polymorphism, Reference proteome, Repeat, SH3 domainfocal adhesions, plasma membrane
Q53QZ3ARHGAP15YesNoNoYesNo3D-structure, Complete proteome, Cytoplasm, GTPase activation, Membrane, Phosphoprotein, Reference proteomecytosolic
Q68EM7ARHGAP17RICH1YesNoNoNoNoAlternative splicing, Cell junction, Complete proteome, Cytoplasm, GTPase activation, Membrane, Phosphoprotein, Reference proteome, SH3-binding, Tight junctionplasma membrane
Q8N392ARHGAP18YesNoNoNoNoAlternative splicing, Complete proteome, Cytoplasm, GTPase activation, Phosphoprotein, Polymorphism, Reference proteomecytosolic
Q14CB8ARHGAP19YesNoYesNoNoAcetylation, Alternative splicing, Complete proteome, GTPase activation, Nucleus, Phosphoprotein, Polymorphism, Reference proteomenucleus
Q9P2F6ARHGAP20KIAA1391YesNoYesYesYes3D-structure, Alternative splicing, Chromosomal rearrangement, Complete proteome, GTPase activation, Phosphoprotein, Polymorphism, Reference proteome, Tumor suppressorplasma membrane
Q5T5U3ARHGAP21ARHGAP10, KIAA1424YesNoYesNoNo3D-structure, Alternative splicing, Cell junction, Complete proteome, Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, GTPase activation, Golgi apparatus, Isopeptide bond, Membrane, Methylation, Phosphoprotein, Polymorphism, Reference proteome, Ubl conjugationgolgi, plasma membrane
Q7Z5H3ARHGAP22RHOGAP2YesNoYesYesYesAlternative splicing, Angiogenesis, Coiled coil, Complete proteome, Cytoplasm, Developmental protein, Differentiation, GTPase activation, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Transcription, Transcription regulationfocal adhesions, plasma membrane
Q9P227ARHGAP23KIAA1501YesNoYesYesNoAlternative splicing, Complete proteome, GTPase activation, Isopeptide bond, Phosphoprotein, Reference proteome, Ubl conjugationfocal adhesions, plasma membrane
Q8N264ARHGAP24FILGAPYesNoNoNoNoAlternative splicing, Angiogenesis, Cell junction, Cell projection, Coiled coil, Complete proteome, Cytoplasm, Cytoskeleton, Developmental protein, Differentiation, GTPase activation, Phosphoprotein, Reference proteomeactin
P42331ARHGAP25KIAA0053YesNoNoNoNo3D-structure, Alternative splicing, Coiled coil, Complete proteome, GTPase activation, Phosphoprotein, Polymorphism, Reference proteomecytosolic
Q9UNA1ARHGAP26GRAF, KIAA0621, OPHN1LYesNoYesNoNo3D-structure, Alternative splicing, Cell junction, Chromosomal rearrangement, Complete proteome, Cytoplasm, Cytoskeleton, Disease mutation, GTPase activation, Proto-oncogene, Reference proteome, SH3 domainendoplasmic reticulum
Q6ZUM4ARHGAP27CAMGAP1, SH3D20YesNoNoYesNo3D-structure, Alternative splicing, Complete proteome, Cytoplasm, Endocytosis, GTPase activation, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Repeat, SH3 domaincytosolic
Q9P2N2ARHGAP28KIAA1314YesNoYesNoNoAlternative splicing, Complete proteome, GTPase activation, Phosphoprotein, Polymorphism, Reference proteomeactin
Q52LW3ARHGAP29PARG1YesNoYesNoNoAlternative splicing, Coiled coil, Complete proteome, Direct protein sequencing, GTPase activation, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Zinc, Zinc-fingeractin, plasma membrane
Q7Z6I6ARHGAP30YesNoYesYesYesAlternative splicing, Complete proteome, Cytoplasmic vesicle, GTPase activation, Phosphoprotein, Polymorphism, Reference proteomecytosolic
Q2M1Z3ARHGAP31CDGAP, KIAA1204YesNoYesYesYesCell junction, Cell projection, Complete proteome, GTPase activation, Phosphoprotein, Polymorphism, Reference proteomefocal adhesions, nucleus
A7KAX9ARHGAP32GRIT, KIAA0712, RICSYesNoNoNoNo3D-structure, Alternative splicing, Cell junction, Cell membrane, Cell projection, Complete proteome, Cytoplasm, Endoplasmic reticulum, Endosome, GTPase activation, Golgi apparatus, Membrane, Methylation, Phosphoprotein, Postsynaptic cell membrane, Reference proteome, SH3 domain, Synapseplasma membrane, puncta
O14559ARHGAP33SNX26, TCGAPYesNoNoYesNoAlternative splicing, Complete proteome, GTPase activation, Methylation, Phosphoprotein, Protein transport, Reference proteome, SH3 domain, Transportactin, basal membrane filaments, plasma membrane
Q9NRY4ARHGAP35GRF1, GRLF1, KIAA1722, P190A, p190ARHOGAPYesNoYesYesNo3D-structure, Cell membrane, Cell projection, Complete proteome, Cytoplasm, Cytoskeleton, DNA-binding, GTP-binding, GTPase activation, Lipid-binding, Membrane, Nucleotide-binding, Nucleus, Phosphoprotein, Reference proteome, Repeat, Repressor, Transcription, Transcription regulationactin, focal adhesions
Q6ZRI8ARHGAP36YesNoNoNoNoAlternative splicing, Complete proteome, GTPase activation, Reference proteome, Signallysosomes, plasma membrane, vesicles
Q9C0H5ARHGAP39KIAA1688YesNoNoYesYesAcetylation, Alternative splicing, Complete proteome, Nucleus, Phosphoprotein, Reference proteome, Repeatfocal adhesions, nucleus, plasma membrane
Q5TG30ARHGAP40C20orf95YesNoYesNoYesComplete proteome, GTPase activation, Polymorphism, Reference proteomecytosolic
A6NI28ARHGAP42GRAF3YesNoNoNoNoCoiled coil, Complete proteome, GTPase activation, Phosphoprotein, Reference proteome, SH3 domainactin
Q17R89ARHGAP44KIAA0672, RICH2YesNoNoYesNoAlternative splicing, Cell junction, Cell projection, Complete proteome, Endosome, Exocytosis, GTPase activation, Phosphoprotein, Polymorphism, Reference proteome, Synapsecytosolic
Q92619ARHGAP45HMHA1, KIAA0223YesNoNoNoNo3D-structure, Alternative splicing, Cell membrane, Cell projection, Coiled coil, Complete proteome, Cytoplasm, Direct protein sequencing, GTPase activation, Membrane, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Zinc, Zinc-fingercytosolic
Q92888ARHGEF1NoYesYesNoNo3D-structure, Alternative splicing, Coiled coil, Complete proteome, Cytoplasm, GTPase activation, Guanine-nucleotide releasing factor, Membrane, Phosphoprotein, Polymorphism, Reference proteomecytosolic
Q92974ARHGEF2KIAA0651, LFP40NoYesYesNoNo3D-structure, Acetylation, Alternative splicing, Cell cycle, Cell division, Cell junction, Cell membrane, Cell projection, Coiled coil, Complete proteome, Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Developmental protein, Differentiation, Golgi apparatus, Guanine-nucleotide releasing factor, Immunity, Innate immunity, Membrane, Mental retardation, Metal-binding, Microtubule, Mitosis, Neurogenesis, Phosphoprotein, Reference proteome, Tight junction, Zinc, Zinc-fingertubulin
Q9NR81ARHGEF3NoYesYesNoNoAlternative splicing, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteomenucleus, plasma membrane
Q9NR80ARHGEF4KIAA1112NoYesYesNoYes3D-structure, Alternative splicing, Cell membrane, Cell projection, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Membrane, Polymorphism, Reference proteome, SH3 domaincytosolic
Q12774ARHGEF5TIMNoYesYesNoNoAlternative splicing, Cell junction, Cell projection, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Lipid-binding, Methylation, Nucleus, Phosphoprotein, Proto-oncogene, Reference proteome, SH3 domaincytosolic
Q15052ARHGEF6COOL2, KIAA0006, PIXANoYesNoNoNo3D-structure, Alternative splicing, Cell projection, Complete proteome, Guanine-nucleotide releasing factor, Mental retardation, Phosphoprotein, Polymorphism, Reference proteome, SH3 domainfocal adhesions
Q14155ARHGEF7COOL1, KIAA0142, P85SPR, PAK3BP, PIXBNoYesNoNoNo3D-structure, Acetylation, Alternative splicing, Cell junction, Cell projection, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Neurogenesis, Phosphoprotein, Polymorphism, Reference proteome, SH3 domainfocal adhesions
O43307ARHGEF9ARHDH9, KIAA0424NoYesNoNoYes3D-structure, Alternative splicing, Complete proteome, Cytoplasm, Disease mutation, Epilepsy, Guanine-nucleotide releasing factor, Phosphoprotein, Reference proteome, SH3 domaincytosolic
O15013ARHGEF10KIAA0294NoYesYesYesYesAlternative splicing, Coiled coil, Complete proteome, Disease mutation, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteomecytosolic
Q9HCE6ARHGEF10LGRINCHGEF, KIAA1626NoYesNoNoNoAlternative splicing, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteomecytosolic
O15085ARHGEF11KIAA0380NoYesYesNoNo3D-structure, Alternative splicing, Coiled coil, Complete proteome, Cytoplasm, GTPase activation, Guanine-nucleotide releasing factor, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Ubl conjugationactin, plasma membrane, vesicles
Q9NZN5ARHGEF12KIAA0382, LARGNoYesYesNoNo3D-structure, Acetylation, Alternative splicing, Chromosomal rearrangement, Coiled coil, Complete proteome, Cytoplasm, GTPase activation, Guanine-nucleotide releasing factor, Membrane, Phosphoprotein, Polymorphism, Proto-oncogene, Reference proteomecytosolic
O94989ARHGEF15KIAA0915NoYesYesNoYesCell projection, Complete proteome, GTPase activation, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteome, Ubl conjugationactin
Q5VV41ARHGEF16EPHEXIN4, NBRNoYesNoNoNo3D-structure, Acetylation, Alternative splicing, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteome, SH3 domaincytosolic, vesicles
Q96PE2ARHGEF17KIAA0337, TEM4NoYesYesNoNoComplete proteome, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteomeactin, plasma membrane, vesicles
Q6ZSZ5ARHGEF18KIAA0521NoYesNoNoNoAlternative splicing, Cell membrane, Coiled coil, Complete proteome, Cytoplasm, Cytoskeleton, Disease mutation, Guanine-nucleotide releasing factor, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Retinitis pigmentosaactin
Q8IW93ARHGEF19NoYesYesNoNoAlternative splicing, Complete proteome, GTPase activation, Guanine-nucleotide releasing factor, Polymorphism, Reference proteome, SH3 domainfocal adhesions, plasma membrane
Q86VW2ARHGEF25GEFTNoYesYesNoNo3D-structure, Alternative splicing, Cell membrane, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Membrane, Polymorphism, Reference proteomeplasma membrane
Q96DR7ARHGEF26SGEFNoYesNoNoYesAlternative splicing, Cell projection, Complete proteome, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteome, SH3 domainactin
Q8N1W1ARHGEF28KIAA1998, RGNEFNoYesYesNoNo3D-structure, Alternative splicing, Cell membrane, Coiled coil, Complete proteome, Cytoplasm, Differentiation, Guanine-nucleotide releasing factor, Membrane, Metal-binding, Phosphoprotein, Polymorphism, RNA-binding, Reference proteome, Zinc, Zinc-fingercytosolic
Q8N4T4ARHGEF39C9orf100NoYesNoNoNoAlternative splicing, Cell membrane, Complete proteome, Guanine-nucleotide releasing factor, Membrane, Polymorphism, Reference proteomefocal adhesions, plasma membrane
Q8TER5ARHGEF40SOLONoYesNoNoNoAlternative splicing, Coiled coil, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteomebasal membrane filaments
P11274BCRBCR1, D22S11YesYesNoYesNo3D-structure, ATP-binding, Acetylation, Alternative splicing, Cell junction, Cell membrane, Chromosomal rearrangement, Complete proteome, GTPase activation, Guanine-nucleotide releasing factor, Kinase, Membrane, Methylation, Nucleotide-binding, Phosphoprotein, Polymorphism, Postsynaptic cell membrane, Proto-oncogene, Reference proteome, Serine/threonine-protein kinase, Synapse, Transferaseactin, plasma membrane
P15882CHN1ARHGAP2, CHNYesNoNoYesNo3D-structure, Acetylation, Alternative splicing, Complete proteome, Disease mutation, GTPase activation, Metal-binding, Neurogenesis, Phosphoprotein, Reference proteome, SH2 domain, Zinc, Zinc-fingercytosolic, endomembranes
P52757CHN2ARHGAP3, BCHYesNoNoYesNo3D-structure, Alternative splicing, Complete proteome, GTPase activation, Membrane, Metal-binding, Polymorphism, Reference proteome, SH2 domain, Zinc, Zinc-fingerfocal adhesions
Q5TB30DEPDC1YesNoNoNoNo3D-structure, Alternative splicing, Complete proteome, GTPase activation, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repressor, Transcription, Transcription regulationcytosolic
Q8WUY9DEPDC1BXTP8YesNoNoNoNoAlternative splicing, Complete proteome, GTPase activation, Phosphoprotein, Polymorphism, Reference proteomeplasma membrane
Q96QB1DLC1ARHGAP7, KIAA1723, STARD12YesNoYesNoNo3D-structure, Alternative promoter usage, Alternative splicing, Cell junction, Complete proteome, Cytoplasm, GTPase activation, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Tumor suppressorfocal adhesions
Q6XZF7DNMBPKIAA1010NoYesNoNoYes3D-structure, Acetylation, Alternative splicing, Cell junction, Coiled coil, Complete proteome, Cytoplasm, Cytoskeleton, Golgi apparatus, Phosphoprotein, Polymorphism, Reference proteome, Repeat, SH3 domain, Synapsecytosolic, plasma membrane
Q14185DOCK1NoYesNoNoNo3D-structure, Apoptosis, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Membrane, Phagocytosis, Phosphoprotein, Polymorphism, Reference proteome, SH3 domain, SH3-bindingactin, focal adhesions, plasma membrane
Q92608DOCK2KIAA0209NoYesNoNoNo3D-structure, Acetylation, Alternative splicing, Complete proteome, Cytoplasm, Cytoskeleton, Disease mutation, Guanine-nucleotide releasing factor, Membrane, Phosphoprotein, Polymorphism, Reference proteome, SH3 domaincytosolic
Q8IZD9DOCK3KIAA0299, MOCANoYesNoYesNoChromosomal rearrangement, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Phosphoprotein, Reference proteome, SH3 domain, SH3-bindingfocal adhesions, plasma membrane
Q8N1I0DOCK4KIAA0716NoYesNoNoNoAlternative splicing, Cell membrane, Cell projection, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Membrane, Phosphoprotein, Polymorphism, Proto-oncogene, Reference proteome, SH3 domain, SH3-bindingcytosolic
Q9H7D0DOCK5NoYesNoNoNoAcetylation, Alternative splicing, Cell membrane, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Membrane, Phosphoprotein, Polymorphism, Reference proteome, SH3 domainfocal adhesions
Q96HP0DOCK6KIAA1395NoYesNoNoNoComplete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Methylation, Phosphoprotein, Polymorphism, Reference proteomecytosolic
Q96N67DOCK7KIAA1771NoYesNoNoNoAcetylation, Alternative splicing, Cell projection, Coiled coil, Complete proteome, Developmental protein, Differentiation, Epilepsy, Guanine-nucleotide releasing factor, Methylation, Neurogenesis, Phosphoprotein, Polymorphism, Reference proteomecytosolic
Q8NF50DOCK8NoYesNoNoNoAlternative splicing, Cell membrane, Cell projection, Chromosomal rearrangement, Complete proteome, Cytoplasm, Disease mutation, Guanine-nucleotide releasing factor, Membrane, Mental retardation, Phosphoprotein, Polymorphism, Reference proteomecytosolic
Q9BZ29DOCK9KIAA1058, ZIZ1NoYesNoNoNo3D-structure, Alternative splicing, Coiled coil, Complete proteome, Guanine-nucleotide releasing factor, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Repeatcytosolic
Q96BY6DOCK10KIAA0694, ZIZ3NoYesNoYesNoAcetylation, Alternative splicing, Cell projection, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Nucleus, Phosphoprotein, Reference proteomeplasma membrane
Q5JSL3DOCK11ZIZ2NoYesNoNoNoComplete proteome, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteomecytosolic
Q9H8V3ECT2NoYesYesNoNo3D-structure, Acetylation, Alternative splicing, Cell cycle, Cell division, Cell junction, Complete proteome, Cytoplasm, Cytoskeleton, Differentiation, Guanine-nucleotide releasing factor, Isopeptide bond, Neurogenesis, Nucleus, Oncogene, Phosphoprotein, Polymorphism, Protein transport, Reference proteome, Repeat, Tight junction, Transport, Ubl conjugationnucleus, plasma membrane
Q008S8ECT2LC6orf91, LFDHNoYesNoNoNoComplete proteome, Guanine-nucleotide releasing factor, Polymorphism, Reference proteomefocal adhesions
O94988FAM13AFAM13A1, KIAA0914YesNoNoYesNoAlternative splicing, Coiled coil, Complete proteome, GTPase activation, Phosphoprotein, Polymorphism, Reference proteomecytosolic
Q9NYF5FAM13BC5orf5, FAM13B1YesNoNoYesYesAlternative splicing, Complete proteome, GTPase activation, Polymorphism, Reference proteomecytosolic
Q9Y4F1FARP1CDEP, PLEKHC2NoYesNoNoNo3D-structure, Alternative splicing, Cell junction, Cell membrane, Cell projection, Complete proteome, Cytoplasm, Developmental protein, Guanine-nucleotide releasing factor, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Synapse, Synaptosomeplasma membrane
O94887FARP2KIAA0793, PLEKHC3NoYesNoNoNoAlternative splicing, Complete proteome, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteome, Repeatfocal adhesions, plasma membrane
P98174FGD1FGDY, ZFYVE3NoYesNoNoYesCell projection, Complete proteome, Cytoplasm, Cytoskeleton, Disease mutation, Guanine-nucleotide releasing factor, Metal-binding, Phosphoprotein, Reference proteome, Repeat, Zinc, Zinc-fingeractin
Q7Z6J4FGD2ZFYVE4NoYesNoNoYesAlternative splicing, Cell membrane, Cell projection, Complete proteome, Cytoplasm, Cytoskeleton, Endosome, Guanine-nucleotide releasing factor, Membrane, Metal-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Zinc, Zinc-fingeractin
Q5JSP0FGD3ZFYVE5NoYesNoNoYes3D-structure, Alternative splicing, Complete proteome, Cytoplasm, Cytoskeleton, Guanine-nucleotide releasing factor, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Zinc, Zinc-fingercytosolic
Q96M96FGD4FRABP, ZFYVE6NoYesNoNoYesActin-binding, Alternative splicing, Cell projection, Charcot-Marie-Tooth disease, Complete proteome, Cytoplasm, Cytoskeleton, Disease mutation, Guanine-nucleotide releasing factor, Metal-binding, Neurodegeneration, Neuropathy, Phosphoprotein, Reference proteome, Repeat, Zinc, Zinc-fingeractin, vesicles
Q6ZNL6FGD5ZFYVE23NoYesNoYesNo3D-structure, Alternative splicing, Cell membrane, Cell projection, Complete proteome, Cytoplasm, Cytoskeleton, Endoplasmic reticulum, Endosome, Golgi apparatus, Guanine-nucleotide releasing factor, Membrane, Metal-binding, Polymorphism, Reference proteome, Repeat, Zinc, Zinc-fingerplasma membrane
Q6ZV73FGD6KIAA1362, ZFYVE24NoYesNoNoNoAlternative splicing, Complete proteome, Cytoplasm, Cytoskeleton, Guanine-nucleotide releasing factor, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Zinc, Zinc-fingeractin
Q9P107GMIPYesNoYesYesYes3D-structure, Alternative splicing, Coiled coil, Complete proteome, GTPase activation, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Zinc, Zinc-fingerpuncta
P32019INPP5BOCRL2YesNoNoNoNo3D-structure, Alternative splicing, Complete proteome, Cytoplasm, Cytoplasmic vesicle, Direct protein sequencing, Endosome, Golgi apparatus, Hydrolase, Lipoprotein, Magnesium, Membrane, Metal-binding, Methylation, Polymorphism, Prenylation, Reference proteomevesicles
Q15811ITSN1ITSN, SH3D1ANoYesNoNoNo3D-structure, Alternative splicing, Calcium, Cell junction, Cell projection, Coated pit, Coiled coil, Complete proteome, Endocytosis, Host-virus interaction, Membrane, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, SH3 domain, Synapse, Synaptosomefocal adhesions, vesicles
Q9NZM3ITSN2KIAA1256, SH3D1B, SWAPNoYesNoNoNo3D-structure, Alternative splicing, Calcium, Coiled coil, Complete proteome, Cytoplasm, Differentiation, Endocytosis, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, SH3 domainactin, focal adhesions, vesicles
O60229KALRNDUET, DUO, HAPIP, TRADNoYesNoNoNoATP-binding, Alternative initiation, Alternative splicing, Complete proteome, Cytoplasm, Cytoskeleton, Disulfide bond, Guanine-nucleotide releasing factor, Immunoglobulin domain, Kinase, Magnesium, Metal-binding, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, SH3 domain, Serine/threonine-protein kinase, Transferasefocal adhesions, plasma membrane
P10911MCF2DBLNoYesYesYesYesAlternative splicing, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Membrane, Phosphoprotein, Proto-oncogene, Reference proteomebasal membrane filaments, plasma membrane, vesicles
O15068MCF2LNoYesYesNoYesAlternative splicing, Cell membrane, Coiled coil, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Lipid-binding, Membrane, Phosphoprotein, Proto-oncogene, Reference proteome, SH3 domainplasma membrane, vesicles
Q86YR7MCF2L2DRG, KIAA0861NoYesNoNoNoAlternative splicing, Complete proteome, Diabetes mellitus, Guanine-nucleotide releasing factor, Polymorphism, Reference proteomeplasma membrane, vesicles
B2RTY4MYO9AMYR7YesNoYesNoNoATP-binding, Actin-binding, Alternative splicing, Coiled coil, Complete proteome, GTPase activation, Membrane, Metal-binding, Motor protein, Myosin, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Zinc, Zinc-fingeractin
Q13459MYO9BMYR5YesNoYesYesYes3D-structure, ATP-binding, Acetylation, Actin-binding, Alternative splicing, Calmodulin-binding, Coiled coil, Complete proteome, Cytoplasm, Cytoskeleton, GTPase activation, Metal-binding, Motor protein, Myosin, Nucleotide-binding, Phosphoprotein, Reference proteome, Repeat, Zinc, Zinc-fingeractin
Q7Z628NET1ARHGEF8NoYesYesNoNo3D-structure, Acetylation, Alternative splicing, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Nucleus, Phosphoprotein, Polymorphism, Proto-oncogene, Reference proteomenucleus, plasma membrane
Q8N5V2NGEFNoYesYesNoNoAlternative splicing, Cell projection, Complete proteome, Cytoplasm, Developmental protein, Differentiation, Guanine-nucleotide releasing factor, Membrane, Neurogenesis, Phosphoprotein, Polymorphism, Reference proteome, SH3 domaincytosolic
Q01968OCRLINPP5F, OCRL1YesNoNoNoNo3D-structure, Alternative splicing, Cataract, Cell projection, Ciliopathy, Cilium, Cilium biogenesis/degradation, Coated pit, Complete proteome, Cytoplasmic vesicle, Disease mutation, Endosome, Golgi apparatus, Hydrolase, Membrane, Reference proteomefocal adhesions, vesicles
O60890OPHN1YesNoNoNoNoAlternative splicing, Cell junction, Cell projection, Complete proteome, Cytoplasm, Disease mutation, Endocytosis, GTPase activation, Mental retardation, Neurogenesis, Polymorphism, Reference proteome, Synapseactin
P27986PIK3R1GRB1YesNoNoNoNo3D-structure, Acetylation, Alternative splicing, Complete proteome, Disease mutation, Dwarfism, Host-virus interaction, Phosphoprotein, Polymorphism, Protein transport, Reference proteome, Repeat, SH2 domain, SH3 domain, Stress response, Transport, Ubl conjugationfocal adhesions
O00459PIK3R2YesNoNoNoNo3D-structure, Complete proteome, Disease mutation, Phosphoprotein, Polymorphism, Protein transport, Reference proteome, Repeat, SH2 domain, SH3 domain, Stress response, Transport, Ubl conjugationfocal adhesions
Q9ULL1PLEKHG1KIAA1209NoYesNoNoYesComplete proteome, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteomeactin, focal adhesions
Q9H7P9PLEKHG2NoYesNoNoNoAlternative splicing, Complete proteome, Disease mutation, Guanine-nucleotide releasing factor, Leukodystrophy, Mental retardation, Phosphoprotein, Polymorphism, Reference proteome, Tumor suppressoractin
A1L390PLEKHG3KIAA0599NoYesNoNoYesAlternative splicing, Complete proteome, Methylation, Phosphoprotein, Polymorphism, Reference proteomeactin
Q58EX7PLEKHG4PRTPHN1NoYesNoNoYesAlternative splicing, Complete proteome, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteomecytosolic
Q96PX9PLEKHG4BKIAA1909NoYesNoNoYesComplete proteome, Polymorphism, Reference proteomeactin
O94827PLEKHG5KIAA0720NoYesYesNoNoAlternative splicing, Cell junction, Cell membrane, Cell projection, Charcot-Marie-Tooth disease, Complete proteome, Cytoplasm, Disease mutation, Membrane, Neurodegeneration, Neuropathy, Phosphoprotein, Polymorphism, Reference proteomeplasma membrane
Q3KR16PLEKHG6NoYesYesYesNoAlternative splicing, Cell projection, Complete proteome, Cytoplasm, Cytoskeleton, GTPase activation, Polymorphism, Reference proteomeactin
Q6ZR37PLEKHG7NoYesNoNoNoComplete proteome, Polymorphism, Reference proteomevesicles
Q8TCU6PREX1KIAA1415NoYesNoYesNo3D-structure, Alternative splicing, Cell membrane, Complete proteome, Cytoplasm, Direct protein sequencing, Guanine-nucleotide releasing factor, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Repeatcytosolic
Q70Z35PREX2DEPDC2NoYesYesYesYesAlternative splicing, Complete proteome, Guanine-nucleotide releasing factor, Polymorphism, Reference proteome, Repeatcytosolic
Q9H0H5RACGAP1KIAA1478, MGCRACGAPYesNoNoYesNo3D-structure, Acetylation, Cell cycle, Cell division, Cell membrane, Coiled coil, Complete proteome, Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Developmental protein, Differentiation, GTPase activation, Ion transport, Isopeptide bond, Lipid-binding, Membrane, Metal-binding, Microtubule, Nucleus, Phosphoprotein, Reference proteome, Spermatogenesis, Transport, Ubl conjugation, Zinc, Zinc-fingernucleus, plasma membrane
Q15311RALBP1RLIP1, RLIP76YesNoNoYesNo3D-structure, Acetylation, Complete proteome, Direct protein sequencing, GTPase activation, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Transportcytosolic
Q13972RASGRF1NoYesNoNoNoAlternative splicing, Complete proteome, Guanine-nucleotide releasing factor, Phosphoprotein, Reference proteome, Repeat, Ubl conjugationcytosolic
O14827RASGRF2GRF2NoYesYesYesYesCalcium, Calmodulin-binding, Cell membrane, Coiled coil, Complete proteome, Cytoplasm, Endoplasmic reticulum, Guanine-nucleotide releasing factor, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Ubl conjugationnucleus
Q9Y3L3SH3BP1YesNoNoYesNo3D-structure, Alternative initiation, Alternative splicing, Cell junction, Cell projection, Complete proteome, Cytoplasm, GTPase activation, Nucleus, Phagocytosis, Phosphoprotein, Polymorphism, Reference proteome, SH3-binding, Tight junctionactin
Q07889SOS1NoYesNoNoNo3D-structure, Alternative splicing, Complete proteome, Disease mutation, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteomefocal adhesions
Q07890SOS2NoYesNoNoNoAlternative splicing, Complete proteome, Disease mutation, Guanine-nucleotide releasing factor, Methylation, Polymorphism, Reference proteomefocal adhesions
Q96N96SPATA13NoYesNoNoYesAlternative splicing, Cell membrane, Cell projection, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Membrane, Phosphoprotein, Polymorphism, Reference proteome, SH3 domainplasma membrane
Q7Z6B7SRGAP1ARHGAP13, KIAA1304YesNoNoYesNoAlternative splicing, Coiled coil, Complete proteome, Disease mutation, GTPase activation, Phosphoprotein, Reference proteome, SH3 domainactin, focal adhesions, plasma membrane, puncta
O75044SRGAP2ARHGAP34, FNBP2, KIAA0456, SRGAP2AYesNoNoYesYes3D-structure, Cell junction, Cell membrane, Cell projection, Chromosomal rearrangement, Coiled coil, Complete proteome, Cytoplasm, Cytoplasmic vesicle, GTPase activation, Membrane, Methylation, Neurogenesis, Nucleus, Phosphoprotein, Polymorphism, Postsynaptic cell membrane, Reference proteome, SH3 domain, Synapseplasma membrane, puncta
O43295SRGAP3ARHGAP14, KIAA0411, KIAA1156, MEGAP, SRGAP2YesNoNoYesNoAlternative splicing, Chromosomal rearrangement, Coiled coil, Complete proteome, GTPase activation, Phosphoprotein, Polymorphism, Reference proteome, SH3 domainfocal adhesions
Q92502STARD8DLC3, KIAA0189YesNoYesNoYesAlternative splicing, Cell junction, Complete proteome, GTPase activation, Methylation, Phosphoprotein, Polymorphism, Reference proteomefocal adhesions
Q9Y3M8STARD13DLC2, GT650YesNoYesNoNo3D-structure, Acetylation, Alternative splicing, Complete proteome, Cytoplasm, GTPase activation, Lipid droplet, Membrane, Mitochondrion, Phosphoprotein, Polymorphism, Reference proteome, Tumor suppressorfocal adhesions
Q6ZW31SYDE1YesNoNoNoNoAlternative splicing, Complete proteome, GTPase activation, Phosphoprotein, Polymorphism, Reference proteomeactin, focal adhesions
Q5VT97SYDE2YesNoNoYesNoAlternative splicing, Complete proteome, GTPase activation, Phosphoprotein, Polymorphism, Reference proteomefocal adhesions, nucleus
Q8N103TAGAPTAGAP1YesNoYesYesNoAlternative splicing, Complete proteome, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteomecytosolic
Q13009TIAM1NoYesNoYesNo3D-structure, Alternative splicing, Cell junction, Cell membrane, Complete proteome, Guanine-nucleotide releasing factor, Lipid-binding, Lipoprotein, Membrane, Myristate, Phosphoprotein, Polymorphism, Reference proteome, Repeatplasma membrane
Q8IVF5TIAM2KIAA2016, STEFNoYesNoYesNoAlternative splicing, Cell projection, Coiled coil, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Lipoprotein, Myristate, Phosphoprotein, Polymorphism, Reference proteome, Repeatnuclear membrane, plasma membrane
O75962TRIONoYesNoYesNo3D-structure, ATP-binding, Alternative splicing, Complete proteome, Cytoplasm, Disease mutation, Disulfide bond, Guanine-nucleotide releasing factor, Immunoglobulin domain, Kinase, Mental retardation, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, SH3 domain, Serine/threonine-protein kinase, Transferasebasal membrane filaments, focal adhesions
P15498VAV1VAVNoYesYesYesNo3D-structure, Alternative splicing, Complete proteome, Guanine-nucleotide releasing factor, Metal-binding, Phosphoprotein, Polymorphism, Proto-oncogene, Reference proteome, Repeat, SH2 domain, SH3 domain, Zinc, Zinc-fingerfocal adhesions
P52735VAV2NoYesYesYesNo3D-structure, Alternative splicing, Angiogenesis, Complete proteome, Guanine-nucleotide releasing factor, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, SH2 domain, SH3 domain, Zinc, Zinc-fingercytosolic
Q9UKW4VAV3NoYesYesNoNo3D-structure, Alternative promoter usage, Alternative splicing, Angiogenesis, Complete proteome, Guanine-nucleotide releasing factor, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, SH2 domain, SH3 domain, Zinc, Zinc-fingerfocal adhesions